Patients affected by Parkinson's disease (PD) may present with lower urinary tract (LUT) dysfunction characterized by involuntary detrusor overactivity. We evaluated possible impact of a 2-week course of low frequency 1 Hz repetitive transcranial magnetic stimulation (rTMS) on LUT behavior in eight advanced PD patients complaining of urinary disturbances. We tested the effects of rTMS measuring urodynamic examination and the International Prostate Symptoms Score (IPSS) questionnaire, used for evaluation of subjective LUTS. rTMS was able to improve temporarily LUT behavior in PD patients, increasing bladder capacity and the first sensation of filling phase. Moreover, a reduction of IPSS score was noticed, due to an improvement on filling phase symptoms. The beneficial effects assessed with the IPSS lasted for up to 2 weeks after the end of the stimulation. rTMS seems to be an effective, noninvasive alternative treatment for PD patients with urinary disturbances.

Brusa, L., FINAZZI AGRO', E., Petta, F., Sciobica, F., Torriero, S., Lo Gerfo, E., et al. (2009). Effects of inhibitory rTMS on bladder function in Parkinson's disease patients. MOVEMENT DISORDERS, 24(3), 445-448 [10.1002/mds.22434].

Effects of inhibitory rTMS on bladder function in Parkinson's disease patients

FINAZZI AGRO', ENRICO;STANZIONE, PAOLO;
2009-02-15

Abstract

Patients affected by Parkinson's disease (PD) may present with lower urinary tract (LUT) dysfunction characterized by involuntary detrusor overactivity. We evaluated possible impact of a 2-week course of low frequency 1 Hz repetitive transcranial magnetic stimulation (rTMS) on LUT behavior in eight advanced PD patients complaining of urinary disturbances. We tested the effects of rTMS measuring urodynamic examination and the International Prostate Symptoms Score (IPSS) questionnaire, used for evaluation of subjective LUTS. rTMS was able to improve temporarily LUT behavior in PD patients, increasing bladder capacity and the first sensation of filling phase. Moreover, a reduction of IPSS score was noticed, due to an improvement on filling phase symptoms. The beneficial effects assessed with the IPSS lasted for up to 2 weeks after the end of the stimulation. rTMS seems to be an effective, noninvasive alternative treatment for PD patients with urinary disturbances.
15-feb-2009
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/24 - UROLOGIA
English
Con Impact Factor ISI
Male; Time Factors; Urodynamics; Middle Aged; Female; Questionnaires; Humans; Levodopa; Parkinson Disease; Antiparkinson Agents; Prostatic Neoplasms; Urinary Bladder, Overactive; Aged; Transcranial Magnetic Stimulation; Severity of Illness Index
Brusa, L., FINAZZI AGRO', E., Petta, F., Sciobica, F., Torriero, S., Lo Gerfo, E., et al. (2009). Effects of inhibitory rTMS on bladder function in Parkinson's disease patients. MOVEMENT DISORDERS, 24(3), 445-448 [10.1002/mds.22434].
Brusa, L; FINAZZI AGRO', E; Petta, F; Sciobica, F; Torriero, S; Lo Gerfo, E; Iani, C; Stanzione, P; Koch, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/41414
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