The different roles of D1 and D2 dopamine receptors in LUT behavior have been demonstrated in animal studies. In particular D2 selective agonists and D1 selective antagonists seem to produce a reduction of the bladder capacity in conscious rats. This finding has never been confirmed in human studies. Thus, in this study we investigated the role of D1 and D2 agonists/antagonists on LUT behavior in patients with PD.

Brusa, L., Petta, F., Pisani, A., Miano, R., Stanzione, P., Moschella, V., et al. (2006). Central acute D2 stimulation worsens bladder function in patients with mild Parkinson's disease. THE JOURNAL OF UROLOGY, 175(1), 202-207 [10.1016/S0022-5347(05)00058-3].

Central acute D2 stimulation worsens bladder function in patients with mild Parkinson's disease

PISANI, ANTONIO;MIANO, ROBERTO;STANZIONE, PAOLO;FINAZZI AGRO', ENRICO
2006-01-01

Abstract

The different roles of D1 and D2 dopamine receptors in LUT behavior have been demonstrated in animal studies. In particular D2 selective agonists and D1 selective antagonists seem to produce a reduction of the bladder capacity in conscious rats. This finding has never been confirmed in human studies. Thus, in this study we investigated the role of D1 and D2 agonists/antagonists on LUT behavior in patients with PD.
gen-2006
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/24 - UROLOGIA
English
Con Impact Factor ISI
Dopamine Antagonists; Parkinson Disease; Male; Middle Aged; Female; Urinary Bladder; Severity of Illness Index; Domperidone; Sulpiride; Humans
Brusa, L., Petta, F., Pisani, A., Miano, R., Stanzione, P., Moschella, V., et al. (2006). Central acute D2 stimulation worsens bladder function in patients with mild Parkinson's disease. THE JOURNAL OF UROLOGY, 175(1), 202-207 [10.1016/S0022-5347(05)00058-3].
Brusa, L; Petta, F; Pisani, A; Miano, R; Stanzione, P; Moschella, V; Galati, S; FINAZZI AGRO', E
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/40371
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