The cases are reported of two women patients presenting asymptomatic solitary lesions: one in the anterior tibial region of the right leg, the other on the right arm. The first patient's lesion was 3cm in diameter and had appeared 2years earlier as a translucent oval atrophic patch with a definite border. The second patient presented a whitish area with a lilac ring, 2.5 cm in diameter, which had appeared nearly a year earlier. Both patients had no other similar cutaneous lesions, and their family histories for cutaneous disease were negative. The lesions underwent punch biopsy, and the histopathological findings confirmed the diagnosis of morphea. Laboratory investigations showed no abnormalities. Imiquimod 5% cream was prescribed for 5 consecutive days a week for 16weeks. Clinical and dermoscopic assessment of the lesions was performed before treatment, during follow-up and at treatment end point. No local or systemic side effects were observed during treatment. Following treatment, both patients achieved complete clinical remission of the lesions, with a definitive improvement in the lesions' initial disfiguring features.

Campione, E., Paternò, E., Diluvio, L., Orlandi, A., Bianchi, L., Chimenti, S. (2009). Localized morphea treated with imiquimod 5% and dermoscopic assessment of effectiveness. THE JOURNAL OF DERMATOLOGICAL TREATMENT, 20(1), 10-13 [10.1080/09546630802132668].

Localized morphea treated with imiquimod 5% and dermoscopic assessment of effectiveness

CAMPIONE, ELENA;ORLANDI, AUGUSTO;BIANCHI, LUCA;CHIMENTI, SERGIO
2009-01-01

Abstract

The cases are reported of two women patients presenting asymptomatic solitary lesions: one in the anterior tibial region of the right leg, the other on the right arm. The first patient's lesion was 3cm in diameter and had appeared 2years earlier as a translucent oval atrophic patch with a definite border. The second patient presented a whitish area with a lilac ring, 2.5 cm in diameter, which had appeared nearly a year earlier. Both patients had no other similar cutaneous lesions, and their family histories for cutaneous disease were negative. The lesions underwent punch biopsy, and the histopathological findings confirmed the diagnosis of morphea. Laboratory investigations showed no abnormalities. Imiquimod 5% cream was prescribed for 5 consecutive days a week for 16weeks. Clinical and dermoscopic assessment of the lesions was performed before treatment, during follow-up and at treatment end point. No local or systemic side effects were observed during treatment. Following treatment, both patients achieved complete clinical remission of the lesions, with a definitive improvement in the lesions' initial disfiguring features.
2009
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/35 - MALATTIE CUTANEE E VENEREE
English
Con Impact Factor ISI
Dermoscopy; Imiquimod; Localized morphea
Campione, E., Paternò, E., Diluvio, L., Orlandi, A., Bianchi, L., Chimenti, S. (2009). Localized morphea treated with imiquimod 5% and dermoscopic assessment of effectiveness. THE JOURNAL OF DERMATOLOGICAL TREATMENT, 20(1), 10-13 [10.1080/09546630802132668].
Campione, E; Paternò, E; Diluvio, L; Orlandi, A; Bianchi, L; Chimenti, S
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/39165
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