Several therapeutic modalities have been proposed for the treatment of vitiligo either to achive repigmentation in the lesions or to stabilize the disease. Narrow-band UVB therapy has been shown to be effective and safe for use in the management of vitiligo; its wavelength is not so different from 308 nm XeCl excimer laser radiation. We present an open and uncontrolled pilot study of 24 patients (12 men, 12 women) in whom vitiligous patches were treated twice a week, for 9 months with 308 nm XeCl laser radiation. Seven of the 24 patients showed greater than 75% repigmentation, six patients showed repigmentation of between 25 and 75% and six patients showed less than 25% repigmentation. In five patients no signs of repigmentation were noted. The therapeutic benefit was stable during the 12-month follow-up period. Although these results are promising, treatment has so far been limited to small numbers of patients and a short follow-up period. Other prospective studies are needed to assess the efficacy of this treatment modality.

Esposito, M., Soda, R., Costanzo, A., Chimenti, S. (2004). Treatment of vitiligo with the 308 nm excimer laser. CLINICAL AND EXPERIMENTAL DERMATOLOGY, 29(2), 133-137 [10.1111/j.1365-2230.2004.01477.x].

Treatment of vitiligo with the 308 nm excimer laser

COSTANZO, ANTONIO;CHIMENTI, SERGIO
2004-01-01

Abstract

Several therapeutic modalities have been proposed for the treatment of vitiligo either to achive repigmentation in the lesions or to stabilize the disease. Narrow-band UVB therapy has been shown to be effective and safe for use in the management of vitiligo; its wavelength is not so different from 308 nm XeCl excimer laser radiation. We present an open and uncontrolled pilot study of 24 patients (12 men, 12 women) in whom vitiligous patches were treated twice a week, for 9 months with 308 nm XeCl laser radiation. Seven of the 24 patients showed greater than 75% repigmentation, six patients showed repigmentation of between 25 and 75% and six patients showed less than 25% repigmentation. In five patients no signs of repigmentation were noted. The therapeutic benefit was stable during the 12-month follow-up period. Although these results are promising, treatment has so far been limited to small numbers of patients and a short follow-up period. Other prospective studies are needed to assess the efficacy of this treatment modality.
2004
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/35 - MALATTIE CUTANEE E VENEREE
English
Con Impact Factor ISI
adolescent; adult; article; clinical article; clinical trial; controlled clinical trial; controlled study; disease duration; erythema; excimer laser; female; human; male; priority journal; pruritus; school child; skin pigmentation; treatment outcome; vitiligo; Adolescent; Adult; Child; Dose-Response Relationship, Radiation; Female; Humans; Lasers; Male; Middle Aged; Phototherapy; Pilot Projects; Treatment Outcome; Vitiligo
Esposito, M., Soda, R., Costanzo, A., Chimenti, S. (2004). Treatment of vitiligo with the 308 nm excimer laser. CLINICAL AND EXPERIMENTAL DERMATOLOGY, 29(2), 133-137 [10.1111/j.1365-2230.2004.01477.x].
Esposito, M; Soda, R; Costanzo, A; Chimenti, S
Articolo su rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/33773
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