Molecular and cellular immune activities have a fundamental role in all stages of the atherosclerotic process and in the pathogenesis of cerebrovascular and cardiovascular diseases. Recent studies have demonstrated how chronic infections can support a local and systemic chronic inflammation, leading to the atherosclerotic process. The pathogenic link between infection and cardiovascular and cerebrovascular disease is not completely defined. Some therapeutic strategies, able to influence the persistence of the infections or to modify the inflammatory process, could be useful in primary and secondary vascular disease prevention and in modifying the acute event outcome. (C) 2005 Prous Science. All rights reserved.

Diomedi, M., Leone, G., Renna, A. (2005). The role of chronic infection and inflammation in the pathogenesis of cardiovascular and cerebrovascular disease. DRUGS OF TODAY, 41(11), 745-753 [10.1358/dot.2005.41.11.917342].

The role of chronic infection and inflammation in the pathogenesis of cardiovascular and cerebrovascular disease

DIOMEDI, MARINA;
2005-11-01

Abstract

Molecular and cellular immune activities have a fundamental role in all stages of the atherosclerotic process and in the pathogenesis of cerebrovascular and cardiovascular diseases. Recent studies have demonstrated how chronic infections can support a local and systemic chronic inflammation, leading to the atherosclerotic process. The pathogenic link between infection and cardiovascular and cerebrovascular disease is not completely defined. Some therapeutic strategies, able to influence the persistence of the infections or to modify the inflammatory process, could be useful in primary and secondary vascular disease prevention and in modifying the acute event outcome. (C) 2005 Prous Science. All rights reserved.
nov-2005
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/26 - NEUROLOGIA
English
Con Impact Factor ISI
amyloid A protein; antibiotic agent; C reactive protein; CagA protein; fibrinogen; heat shock protein 60; interleukin 6; messenger RNA; plasminogen activator inhibitor 1; tumor necrosis factor alpha; antibody response; artery intima proliferation; atherogenesis; atherosclerosis; bacterial colonization; cardiovascular disease; cardiovascular risk; cell activation; cellular immunity; cerebrovascular disease; Chlamydophila pneumoniae; chronic inflammation; cytokine release; Cytomegalovirus; disease marker; heart infarction; Helicobacter pylori; human; immune response; infection; neuroprotection; pathogenesis; prognosis; review; risk factor; stroke; thrombocyte adhesion; virus infection; Bacterial Infections; Cardiovascular Diseases; Cerebrovascular Disorders; Chronic Disease; Humans; Inflammation; Models, Biological; Virus Diseases
Diomedi, M., Leone, G., Renna, A. (2005). The role of chronic infection and inflammation in the pathogenesis of cardiovascular and cerebrovascular disease. DRUGS OF TODAY, 41(11), 745-753 [10.1358/dot.2005.41.11.917342].
Diomedi, M; Leone, G; Renna, A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/32835
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