The role of inflammatory adipokines has clear mechanistic effects in the promotion of both DM2 and cardiovascular diseases (CVDs), but it is unknown to what extent atherosclerosis-related inflammation might promote defects of glucose metabolism. The purpose of this study was to test the hypothesis that in subjects with atherosclerotic vascular disease and no previous medical record of type 2 diabetes mellitus (DM2), the diagnosis of occult impaired glucose regulation (IGR) is related to the severity of atherosclerosis, measured as the single or combined presence of an history of coronary artery disease (CAD), carotid atherosclerosis (Car-ATS) and peripheral artery disease (PAD).
Rizza, S., Cardellini, M., Martelli, E., Porzio, O., Pecchioli, C., Nicolucci, A., et al. (2010). Occult impaired glucose regulation in patients with atherosclerosis is associated to the number of affected vascular districts and inflammation. ATHEROSCLEROSIS, 212(1), 316-320 [10.1016/j.atherosclerosis.2010.05.017].
Occult impaired glucose regulation in patients with atherosclerosis is associated to the number of affected vascular districts and inflammation
RIZZA, STEFANO;CARDELLINI, MARINA;MARTELLI, EUGENIO;PORZIO, OTTAVIA;LAURO, DAVIDE;IPPOLITI, ARNALDO;ROMEO, FRANCESCO;LAURO, RENATO;FEDERICI, MASSIMO
2010-09-01
Abstract
The role of inflammatory adipokines has clear mechanistic effects in the promotion of both DM2 and cardiovascular diseases (CVDs), but it is unknown to what extent atherosclerosis-related inflammation might promote defects of glucose metabolism. The purpose of this study was to test the hypothesis that in subjects with atherosclerotic vascular disease and no previous medical record of type 2 diabetes mellitus (DM2), the diagnosis of occult impaired glucose regulation (IGR) is related to the severity of atherosclerosis, measured as the single or combined presence of an history of coronary artery disease (CAD), carotid atherosclerosis (Car-ATS) and peripheral artery disease (PAD).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
