This report describes the case of a young Romanian patient who developed a severe exacerbation of pulmonary tuberculosis during interferon-alpha treatment for chronic hepatitis D. While this occurrence underscores that clinical guidelines should be applied with caution in immigrants from underdeveloped countries, due to the possible presence of unrecognized or unreported comorbidity, the mechanisms for an interferon-related exacerbation of pulmonary tuberculosis are also examined. We propose that IFN-induced weight loss and anorexia may have played an important role in promoting clinical manifestations of tuberculosis in our patient. © 2007 The British Infection Society.

Telesca, C., Angelico, M., Piccolo, P., Nosotti, L., Morrone, A., Longhi, C., et al. (2007). Interferon-alpha treatment of hepatitis D induces tuberculosis exacerbation in an immigrant, 54(4), e223-e226 [10.1016/j.jinf.2006.12.009].

Interferon-alpha treatment of hepatitis D induces tuberculosis exacerbation in an immigrant

ANGELICO, MARIO;BAIOCCHI, LEONARDO
2007-01-01

Abstract

This report describes the case of a young Romanian patient who developed a severe exacerbation of pulmonary tuberculosis during interferon-alpha treatment for chronic hepatitis D. While this occurrence underscores that clinical guidelines should be applied with caution in immigrants from underdeveloped countries, due to the possible presence of unrecognized or unreported comorbidity, the mechanisms for an interferon-related exacerbation of pulmonary tuberculosis are also examined. We propose that IFN-induced weight loss and anorexia may have played an important role in promoting clinical manifestations of tuberculosis in our patient. © 2007 The British Infection Society.
2007
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/12 - GASTROENTEROLOGIA
English
Con Impact Factor ISI
Hepatitis D; Interferon; Tuberculosis
Telesca, C., Angelico, M., Piccolo, P., Nosotti, L., Morrone, A., Longhi, C., et al. (2007). Interferon-alpha treatment of hepatitis D induces tuberculosis exacerbation in an immigrant, 54(4), e223-e226 [10.1016/j.jinf.2006.12.009].
Telesca, C; Angelico, M; Piccolo, P; Nosotti, L; Morrone, A; Longhi, C; Carbone, M; Baiocchi, L
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/29736
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