Metabolic syndrome (MetS) is a clinical manifestation characterized by a plethora of comorbidities, including hyperglycemia, abdominal obesity, arterial hypertension, and dyslipidemia. All MetS comorbidities participate to induce a low-grade inflammation state and oxidative stress, typical of this syndrome. MetS is related to an increased risk of cardiovascular diseases and early death, with an important impact on health-care costs. For its clinic management a poly-pharmaceutical therapy is often required, but this can cause side effects and reduce the patient's compliance. For this reason, finding a valid and alternative therapeutic strategy, natural and free of side effects, could represent a useful tool in the fight the MetS. In this context, the use of functional foods, and the assumption of natural bioactive compounds (NBCs), could exert beneficial effects on body weight, blood pressure and glucose metabolism control, on endothelial damage, on the improvement of lipid profile, on the inflammatory state, and on oxidative stress. This review focuses on the possible beneficial role of NBCs in the prevention and in the clinical management of MetS and its comorbidities.

Noce, A., Di Lauro, M., Di Daniele, F., Zaitseva, A., Marrone, G., Borboni, P., et al. (2021). Natural Bioactive Compounds Useful in Clinical Management of Metabolic Syndrome. NUTRIENTS, 13(2), 1-37 [10.3390/nu13020630].

Natural Bioactive Compounds Useful in Clinical Management of Metabolic Syndrome

Noce, A;Borboni, P;Di Daniele, N
2021-01-01

Abstract

Metabolic syndrome (MetS) is a clinical manifestation characterized by a plethora of comorbidities, including hyperglycemia, abdominal obesity, arterial hypertension, and dyslipidemia. All MetS comorbidities participate to induce a low-grade inflammation state and oxidative stress, typical of this syndrome. MetS is related to an increased risk of cardiovascular diseases and early death, with an important impact on health-care costs. For its clinic management a poly-pharmaceutical therapy is often required, but this can cause side effects and reduce the patient's compliance. For this reason, finding a valid and alternative therapeutic strategy, natural and free of side effects, could represent a useful tool in the fight the MetS. In this context, the use of functional foods, and the assumption of natural bioactive compounds (NBCs), could exert beneficial effects on body weight, blood pressure and glucose metabolism control, on endothelial damage, on the improvement of lipid profile, on the inflammatory state, and on oxidative stress. This review focuses on the possible beneficial role of NBCs in the prevention and in the clinical management of MetS and its comorbidities.
2021
Pubblicato
Rilevanza internazionale
Articolo
Esperti non anonimi
Settore MED/49 - SCIENZE TECNICHE DIETETICHE APPLICATE
English
metabolic syndrome
natural bioactive compounds
arterial hypertension
diabetes mellitus
dyslipidemia
low-grade inflammatory state
functional foods
Biological Products
Health Care Costs
Humans
Metabolic Syndrome
Quality of Life
Noce, A., Di Lauro, M., Di Daniele, F., Zaitseva, A., Marrone, G., Borboni, P., et al. (2021). Natural Bioactive Compounds Useful in Clinical Management of Metabolic Syndrome. NUTRIENTS, 13(2), 1-37 [10.3390/nu13020630].
Noce, A; Di Lauro, M; Di Daniele, F; Zaitseva, A; Marrone, G; Borboni, P; Di Daniele, N
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/284527
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