(i) To generate a new heterodinucleotide (3TCpPMPA) comprising the drugs lamivudine and tenofovir which have been shown to act synergistically and (ii) to protect macrophages from 'de novo' HIV-1-infection through its administration.

Rossi, L., Franchetti, P., Pierigé, F., Cappellacci, L., Serafini, S., Balestra, E., et al. (2007). Inhibition of HIV-1 replication in macrophages by a heterodinucleotide of lamivudine and tenofovir. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 59(4), 666-675 [10.1093/jac/dkm011].

Inhibition of HIV-1 replication in macrophages by a heterodinucleotide of lamivudine and tenofovir

BALESTRA, EMANUELA;PERNO, CARLO FEDERICO;CALIO', RAFFAELE;
2007-04-01

Abstract

(i) To generate a new heterodinucleotide (3TCpPMPA) comprising the drugs lamivudine and tenofovir which have been shown to act synergistically and (ii) to protect macrophages from 'de novo' HIV-1-infection through its administration.
apr-2007
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/07 - MICROBIOLOGIA E MICROBIOLOGIA CLINICA
English
Con Impact Factor ISI
Virus Replication; Macrophages; Animals; Anti-HIV Agents; Humans; Erythrocytes; Lamivudine; Mice; HIV-1; Chromatography, High Pressure Liquid; Reverse Transcriptase Inhibitors; Indicators and Reagents; Culture Media; Adenine; Phosphonic Acids; Female
Rossi, L., Franchetti, P., Pierigé, F., Cappellacci, L., Serafini, S., Balestra, E., et al. (2007). Inhibition of HIV-1 replication in macrophages by a heterodinucleotide of lamivudine and tenofovir. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 59(4), 666-675 [10.1093/jac/dkm011].
Rossi, L; Franchetti, P; Pierigé, F; Cappellacci, L; Serafini, S; Balestra, E; Perno, Cf; Grifantini, M; Calio', R; Magnani, M
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/27079
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