Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection spreaded rapidly worldwide, as far as it has become a global pandemic. Therefore, the introduction of serological tests for determination of IgM and IgG antibodies has become the main diagnostic tool, useful for tracking the spread of the virus and for consequently allowing its containment. In our study we compared point of care test (POCT) lateral flow immunoassay (FIA) vs automated chemiluminescent immunoassay (CLIA), in order to assess their specificity and sensibility for COVID-19 antibodies detection.

Noce, A., Santoro, M.l., Marrone, G., D'Agostini, C., Amelio, I., Duggento, A., et al. (2020). Serological determinants of COVID-19. BIOLOGY DIRECT, 15(1), 21 [10.1186/s13062-020-00276-1].

Serological determinants of COVID-19

Noce A.;D'Agostini C.;Amelio I.;Duggento A.;Tesauro M.
;
Di Daniele N.
2020-01-01

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection spreaded rapidly worldwide, as far as it has become a global pandemic. Therefore, the introduction of serological tests for determination of IgM and IgG antibodies has become the main diagnostic tool, useful for tracking the spread of the virus and for consequently allowing its containment. In our study we compared point of care test (POCT) lateral flow immunoassay (FIA) vs automated chemiluminescent immunoassay (CLIA), in order to assess their specificity and sensibility for COVID-19 antibodies detection.
2020
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/09 - MEDICINA INTERNA
English
Automated chemiluminescent immunoassay
COVID-19
Laboratory detection
Lateral flow immunoassay
Point of care
SARS-CoV-2
Serological tests
Amino Acid Sequence
COVID-19
Coronavirus Infections
Female
Humans
Immunoassay
Immunoglobulin M
Luminescent Measurements
Male
Middle Aged
Pandemics
Pneumonia, Viral
Protein Domains
Spike Glycoprotein, Coronavirus
Serologic Tests
Noce, A., Santoro, M.l., Marrone, G., D'Agostini, C., Amelio, I., Duggento, A., et al. (2020). Serological determinants of COVID-19. BIOLOGY DIRECT, 15(1), 21 [10.1186/s13062-020-00276-1].
Noce, A; Santoro, Ml; Marrone, G; D'Agostini, C; Amelio, I; Duggento, A; Tesauro, M; Di Daniele, N
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/263925
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