The term idiopathic short stature (ISS) refers to short children with no identifiable disorder of the growth hormone (GH)/insulin like growth factor (IGF) axis and no other endocrine, genetic or organ system disorder. This heterogeneous group of short children without GH deficiency (GHD) includes children with constitutional delay of growth and puberty, familial short stature, or both, as well as those with subtle cartilage and bone dysplasias. In rare cases, ISS is due to IGF molecular abnormalities. In this review we tackle the major challenges in the definition and treatment of ISS.

Pedicelli, S., Peschiaroli, E., Violi, E., Cianfarani, S. (2009). Controversies in the definition and treatment of idiopathic short stature ISS. JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, 1(3), 105-115.

Controversies in the definition and treatment of idiopathic short stature ISS.

CIANFARANI, STEFANO
2009-01-01

Abstract

The term idiopathic short stature (ISS) refers to short children with no identifiable disorder of the growth hormone (GH)/insulin like growth factor (IGF) axis and no other endocrine, genetic or organ system disorder. This heterogeneous group of short children without GH deficiency (GHD) includes children with constitutional delay of growth and puberty, familial short stature, or both, as well as those with subtle cartilage and bone dysplasias. In rare cases, ISS is due to IGF molecular abnormalities. In this review we tackle the major challenges in the definition and treatment of ISS.
2009
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA
Settore MED/13 - ENDOCRINOLOGIA
English
Con Impact Factor ISI
Idiopathic short stature, growth hormone, growth, insulin-like growth factor
Pedicelli, S., Peschiaroli, E., Violi, E., Cianfarani, S. (2009). Controversies in the definition and treatment of idiopathic short stature ISS. JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, 1(3), 105-115.
Pedicelli, S; Peschiaroli, E; Violi, E; Cianfarani, S
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/26102
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