Objectives Synthetic magnetic resonance imaging (SyMRI) allows to obtain different weighted-images using the multiple-dynamic multiple-echo sequence lasting 6 min. The aim is to compare quantitatively and qualitatively synthetic- and conventional MRI in patients with multiple sclerosis (MS) and controls assessing the contrast (C), the signal to noise ratio (SNR), and the contrast to noise ratio (CNR). We evaluated the lesion count and lesion-to-white matter contrast (Cl-WM)in the MS patients. Methods and methods 51 patients underwent synthetic- and conventional MRI. Qualitative analysis was evaluated by assigning scores to all synthetic- and conventional MRI sequences by two neuroradiologists. Lesions were counted in MS patients both in the conventional- and synthetic T2-FLAIR. Regions of interest were placed in the cerebrospinal fluid, in the white- and grey matter. For the sequences were evaluated: C, CNR, and SNR. Results Synthetic T2-FLAIR images are qualitatively inferior. C and CNR were significantly higher in synthetic T1W and T2W images compared to conventional images, but not for T2-FLAIR. The SNR value was always lower in synthetic images than in conventional ones. Conclusions SyMRI can be used in clinical practice because it has a similar diagnostic accuracy which reduces the scanning time compared to the conventional one. However, synthetic T2-FLAIR images need to be improved.

Di Giuliano, F., Minosse, S., Picchi, E., Marfia, G.a., Da Ros, V., Muto, M., et al. (2019). Comparison between synthetic and conventional magnetic resonance imaging in patients with multiple sclerosis and controls. MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE [10.1007/s10334-019-00804-9].

Comparison between synthetic and conventional magnetic resonance imaging in patients with multiple sclerosis and controls

Marfia G. A.;Da Ros V.;Pistolese C. A.;Garaci F.;Floris R.
Membro del Collaboration Group
2019-01-01

Abstract

Objectives Synthetic magnetic resonance imaging (SyMRI) allows to obtain different weighted-images using the multiple-dynamic multiple-echo sequence lasting 6 min. The aim is to compare quantitatively and qualitatively synthetic- and conventional MRI in patients with multiple sclerosis (MS) and controls assessing the contrast (C), the signal to noise ratio (SNR), and the contrast to noise ratio (CNR). We evaluated the lesion count and lesion-to-white matter contrast (Cl-WM)in the MS patients. Methods and methods 51 patients underwent synthetic- and conventional MRI. Qualitative analysis was evaluated by assigning scores to all synthetic- and conventional MRI sequences by two neuroradiologists. Lesions were counted in MS patients both in the conventional- and synthetic T2-FLAIR. Regions of interest were placed in the cerebrospinal fluid, in the white- and grey matter. For the sequences were evaluated: C, CNR, and SNR. Results Synthetic T2-FLAIR images are qualitatively inferior. C and CNR were significantly higher in synthetic T1W and T2W images compared to conventional images, but not for T2-FLAIR. The SNR value was always lower in synthetic images than in conventional ones. Conclusions SyMRI can be used in clinical practice because it has a similar diagnostic accuracy which reduces the scanning time compared to the conventional one. However, synthetic T2-FLAIR images need to be improved.
2019
In corso di stampa
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIA
English
Con Impact Factor ISI
Brain; Magnetic resonance imaging; Multiple sclerosis; Synthetic magnetic resonance imaging
Di Giuliano, F., Minosse, S., Picchi, E., Marfia, G.a., Da Ros, V., Muto, M., et al. (2019). Comparison between synthetic and conventional magnetic resonance imaging in patients with multiple sclerosis and controls. MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE [10.1007/s10334-019-00804-9].
Di Giuliano, F; Minosse, S; Picchi, E; Marfia, Ga; Da Ros, V; Muto, M; Muto, M; Pistolese, Ca; Laghi, A; Garaci, F; Floris, R
Articolo su rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/233363
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