Aging is related to a number of functional and morphological changes leading to progressive decline of the biological functions of an organism. Reactive Oxygen Species (ROS), released by several endogenous and exogenous processes, may cause important oxidative damage toDNA, proteins, and lipids, leading to important cellular dysfunctions.The imbalance between ROS production and antioxidant defenses brings to oxidative stress conditions and, related to accumulation of ROS, aging-associated diseases.The purpose of this review is to provide an overview of the most relevant data reported in literature on the natural compounds, mainly phytochemicals, with antioxidant activity and their potential protective effects on age-related diseases such asmetabolic syndrome, diabetes, cardiovascular disease, cancer, neurodegenerative disease, and chronic inflammation, and possibly lower side effects,when compared to other drugs.
Forni, C., Facchiano, F., Bartoli, M., Pieretti, S., Facchiano, A., D'Arcangelo, D., et al. (2019). Beneficial role of phytochemicals on oxidative stress and age-related diseases. BIOMED RESEARCH INTERNATIONAL(Article ID 9495628) [10.1155/2019/8748253].
Beneficial role of phytochemicals on oxidative stress and age-related diseases
Forni C.Writing – Original Draft Preparation
;Norelli S.Writing – Original Draft Preparation
;Beninati S.Writing – Original Draft Preparation
;
2019-01-01
Abstract
Aging is related to a number of functional and morphological changes leading to progressive decline of the biological functions of an organism. Reactive Oxygen Species (ROS), released by several endogenous and exogenous processes, may cause important oxidative damage toDNA, proteins, and lipids, leading to important cellular dysfunctions.The imbalance between ROS production and antioxidant defenses brings to oxidative stress conditions and, related to accumulation of ROS, aging-associated diseases.The purpose of this review is to provide an overview of the most relevant data reported in literature on the natural compounds, mainly phytochemicals, with antioxidant activity and their potential protective effects on age-related diseases such asmetabolic syndrome, diabetes, cardiovascular disease, cancer, neurodegenerative disease, and chronic inflammation, and possibly lower side effects,when compared to other drugs.| File | Dimensione | Formato | |
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Review Phytochemicals.pdf
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