The tissue inhibitor of metalloproteinase TIMP3 is a stromal protein that restrains the activity of both protease and receptor in the extracellular matrix and has been found to be down-regulated in diabetic nephropathy (DN), the leading cause of end-stage renal disease in developed countries.

Rossi, C., Marzano, V., Consalvo, A., Zucchelli, M., Levi Mortera, S., Casagrande, V., et al. (2018). Proteomic and metabolomic characterization of streptozotocin-induced diabetic nephropathy in TIMP3-deficient mice. ACTA DIABETOLOGICA, 55(2), 1-9 [10.1007/s00592-017-1074-y].

Proteomic and metabolomic characterization of streptozotocin-induced diabetic nephropathy in TIMP3-deficient mice

Casagrande V.;Mavilio M.;Federici M.;Menghini R.;
2018-01-01

Abstract

The tissue inhibitor of metalloproteinase TIMP3 is a stromal protein that restrains the activity of both protease and receptor in the extracellular matrix and has been found to be down-regulated in diabetic nephropathy (DN), the leading cause of end-stage renal disease in developed countries.
2018
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/49 - SCIENZE TECNICHE DIETETICHE APPLICATE
English
Diabetes; Diabetic nephropathy; Kidney; Metabolomics; Proteomics; TIMP3
Rossi, C., Marzano, V., Consalvo, A., Zucchelli, M., Levi Mortera, S., Casagrande, V., et al. (2018). Proteomic and metabolomic characterization of streptozotocin-induced diabetic nephropathy in TIMP3-deficient mice. ACTA DIABETOLOGICA, 55(2), 1-9 [10.1007/s00592-017-1074-y].
Rossi, C; Marzano, V; Consalvo, A; Zucchelli, M; Levi Mortera, S; Casagrande, V; Mavilio, M; Sacchetta, P; Federici, M; Menghini, R; Urbani, A; Ciavardelli, D
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/193919
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