In addition to choosing a state-of-the-art regimen including all-transretinoic and anthracycline chemotherapy, modern management of acute promyelocytic leukemia (APL) implies the adoption of appropriate supportive measures, rapid establishment of an accurate genetic diagnosis, correct assessment of response to therapy and evaluation of the risk of disease recurrence by molecular monitoring. However, the general consensus about this overall strategy for APL treatment still leaves room for a number of controversial issues. In the present article, we review the current standard practice and controversial issues in the treatment of patients with newly diagnosed APL, including the management of special situations such as elderly patients, children and pregnant women.

Sanz, M., LO COCO, F. (2005). Standard practice and controversial issues in front-line therapy of acute promyelocytic leukemia. HAEMATOLOGICA, 90(6), 840-845.

Standard practice and controversial issues in front-line therapy of acute promyelocytic leukemia

LO COCO, FRANCESCO
2005-06-01

Abstract

In addition to choosing a state-of-the-art regimen including all-transretinoic and anthracycline chemotherapy, modern management of acute promyelocytic leukemia (APL) implies the adoption of appropriate supportive measures, rapid establishment of an accurate genetic diagnosis, correct assessment of response to therapy and evaluation of the risk of disease recurrence by molecular monitoring. However, the general consensus about this overall strategy for APL treatment still leaves room for a number of controversial issues. In the present article, we review the current standard practice and controversial issues in the treatment of patients with newly diagnosed APL, including the management of special situations such as elderly patients, children and pregnant women.
giu-2005
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/15 - MALATTIE DEL SANGUE
English
Adolescent; Adult; Aged; Antineoplastic Agents; Female; Hematology; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Pregnancy; Recurrence; Remission Induction; Risk
Sanz, M., LO COCO, F. (2005). Standard practice and controversial issues in front-line therapy of acute promyelocytic leukemia. HAEMATOLOGICA, 90(6), 840-845.
Sanz, M; LO COCO, F
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/162111
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