Forkhead box protein O1 (FoxO1) plays a key role in energy homeostasis, stress response and autophagy and is dysregulated in diabetes and ischemia. We investigated cardiac FoxO1 expression and posttranstranslational modifications after myocardial infarction (MI) and further tested if active posttranstranslational modulation of FoxO1 can alter cardiac remodeling in postischemic heart failure.
Kappel, B., Stohr, R., De Angelis, L., Mavilio, M., Menghini, R., Federici, M. (2016). Posttranslational modulation of FoxO1 contributes to cardiac remodeling in post-ischemic heart failure. ATHEROSCLEROSIS, 249, 148-156 [10.1016/j.atherosclerosis.2016.04.001].
Posttranslational modulation of FoxO1 contributes to cardiac remodeling in post-ischemic heart failure
MENGHINI, ROSSELLA;FEDERICI, MASSIMO
2016-01-01
Abstract
Forkhead box protein O1 (FoxO1) plays a key role in energy homeostasis, stress response and autophagy and is dysregulated in diabetes and ischemia. We investigated cardiac FoxO1 expression and posttranstranslational modifications after myocardial infarction (MI) and further tested if active posttranstranslational modulation of FoxO1 can alter cardiac remodeling in postischemic heart failure.| File | Dimensione | Formato | |
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