Background: Since prehistoric times Southern Italy has been a cultural crossroads of the Mediterranean basin. Genetic data on the peoples of Basilicata and Calabria are scarce and, particularly, no records on mtDNA variability have been published. Aim: In this study mtDNA haplotypes of populations from Basilicata, Calabria and Sicily are compared with those of other Italian and Mediterranean populations, so as to investigate their genetic relationships. Subjects and methods: A total of 341 individuals was analysed for mtDNA in order to provide their classification into haplogroups. Multivariate analysis was used to compare the studied populations with other Mediterranean samples; median-joining network analysis was applied to observe the relationship between the major lineages of the Southern Italians. Results: The haplogroup distribution in the Southern Italian samples falls within the typical pattern of mtDNA variability of Western Eurasia. The comparison with other Mediterranean countries showed a substantial homogeneity of the area, which is probably related to the historic contact through the Mediterranean Sea. Conclusion: The mtDNA analysis demonstrated that Southern Italy displays a typical pattern of Mediterranean basin variability, even though it appears plausible that Southern Italy was less affected by the effects of the Late Glacial Maximum, which reduced genetic diversity in Europe.

Ottoni, C., MARTINEZ-LABARGA, M.c., Vitelli, L., Scano, G., Fabrini, E., Contini, I., et al. (2009). Human mitochondrial DNA variation in Southern Italy. ANNALS OF HUMAN BIOLOGY, 36, 785-811 [10.3109/03014460903198509].

Human mitochondrial DNA variation in Southern Italy

Ottoni, C;MARTINEZ-LABARGA, MARIA CRISTINA;SCANO, GIUSEPPINA;CONTINI, IRENE;RICKARDS, OLGA
2009-01-01

Abstract

Background: Since prehistoric times Southern Italy has been a cultural crossroads of the Mediterranean basin. Genetic data on the peoples of Basilicata and Calabria are scarce and, particularly, no records on mtDNA variability have been published. Aim: In this study mtDNA haplotypes of populations from Basilicata, Calabria and Sicily are compared with those of other Italian and Mediterranean populations, so as to investigate their genetic relationships. Subjects and methods: A total of 341 individuals was analysed for mtDNA in order to provide their classification into haplogroups. Multivariate analysis was used to compare the studied populations with other Mediterranean samples; median-joining network analysis was applied to observe the relationship between the major lineages of the Southern Italians. Results: The haplogroup distribution in the Southern Italian samples falls within the typical pattern of mtDNA variability of Western Eurasia. The comparison with other Mediterranean countries showed a substantial homogeneity of the area, which is probably related to the historic contact through the Mediterranean Sea. Conclusion: The mtDNA analysis demonstrated that Southern Italy displays a typical pattern of Mediterranean basin variability, even though it appears plausible that Southern Italy was less affected by the effects of the Late Glacial Maximum, which reduced genetic diversity in Europe.
Campo DC Valore Lingua
dc.authority.academicField2000 Settore BIO/08 - ANTROPOLOGIA it
dc.authority.ancejournal ANNALS OF HUMAN BIOLOGY -
dc.authority.isicrui Biologia Molecolare e Genetica it
dc.authority.people Ottoni, C -
dc.authority.people MARTINEZ-LABARGA, MARIA CRISTINA it
dc.authority.people Vitelli, L -
dc.authority.people SCANO, GIUSEPPINA it
dc.authority.people Fabrini, E -
dc.authority.people CONTINI, IRENE it
dc.authority.people Biondi, G -
dc.authority.people RICKARDS, OLGA it
dc.cilea.antefix yes it
dc.collection.id.s e291c0df-b2a9-cddb-e053-3a05fe0aa144 *
dc.collection.name 01 - Articolo su rivista *
dc.contributor.appartenenza Dipartimento di Biologia *
dc.contributor.appartenenza.mi 7078 *
dc.contributor.area AREA MIN. 05 - Scienze biologiche *
dc.contributor.area AREA MIN. 05 - Scienze biologiche *
dc.contributor.area AREA MIN. 05 - Scienze biologiche *
dc.contributor.area Non assegnato *
dc.contributor.area AREA MIN. 05 - Scienze biologiche *
dc.date.accessioned 2011-08-30T09:41:04Z -
dc.date.available 2011-08-30T09:41:04Z -
dc.date.issued 2009 -
dc.description.abstracteng Background: Since prehistoric times Southern Italy has been a cultural crossroads of the Mediterranean basin. Genetic data on the peoples of Basilicata and Calabria are scarce and, particularly, no records on mtDNA variability have been published. Aim: In this study mtDNA haplotypes of populations from Basilicata, Calabria and Sicily are compared with those of other Italian and Mediterranean populations, so as to investigate their genetic relationships. Subjects and methods: A total of 341 individuals was analysed for mtDNA in order to provide their classification into haplogroups. Multivariate analysis was used to compare the studied populations with other Mediterranean samples; median-joining network analysis was applied to observe the relationship between the major lineages of the Southern Italians. Results: The haplogroup distribution in the Southern Italian samples falls within the typical pattern of mtDNA variability of Western Eurasia. The comparison with other Mediterranean countries showed a substantial homogeneity of the area, which is probably related to the historic contact through the Mediterranean Sea. Conclusion: The mtDNA analysis demonstrated that Southern Italy displays a typical pattern of Mediterranean basin variability, even though it appears plausible that Southern Italy was less affected by the effects of the Late Glacial Maximum, which reduced genetic diversity in Europe. it
dc.description.allpeople Ottoni, C; MARTINEZ-LABARGA, Mc; Vitelli, L; Scano, G; Fabrini, E; Contini, I; Biondi, G; Rickards, O -
dc.description.allpeopleoriginal Ottoni, C; Martinez-Labarga, C; Vitelli, L; Scano, G; Fabrini, E; Contini, I; Biondi, G; Rickards, O it
dc.description.department Dipartimento di Biologia it
dc.description.fulltext none en
dc.description.numberofauthors 8 -
dc.identifier.citation Ottoni, C., MARTINEZ-LABARGA, M.c., Vitelli, L., Scano, G., Fabrini, E., Contini, I., et al. (2009). Human mitochondrial DNA variation in Southern Italy. ANNALS OF HUMAN BIOLOGY, 36, 785-811 [10.3109/03014460903198509]. it
dc.identifier.doi 10.3109/03014460903198509 it
dc.identifier.isi WOS:000272968100010 en
dc.identifier.pmid 19852679 en
dc.identifier.scopus 2-s2.0-70450240940 -
dc.identifier.uri http://hdl.handle.net/2108/15570 -
dc.identifier.url http://dx.doi.org/10.3109/03014460903198509 it
dc.language.iso eng it
dc.miur.last.status.update 2022-03-23T13:52:27Z *
dc.publisher.country GB it
dc.publisher.name Taylor & Francis it
dc.relation.firstpage 785 it
dc.relation.lastpage 811 it
dc.relation.volume 36 it
dc.subject.keywordseng mtDNA; HVS-I; coding region; genetic diversity; haplogroups it
dc.subject.singlekeyword mtDNA *
dc.subject.singlekeyword HVS-I *
dc.subject.singlekeyword coding region *
dc.subject.singlekeyword genetic diversity *
dc.subject.singlekeyword haplogroups *
dc.title Human mitochondrial DNA variation in Southern Italy it
dc.type Articolo su rivista -
dc.type.circulation Rilevanza internazionale it
dc.type.contribution Articolo it
dc.type.driver info:eu-repo/semantics/article -
dc.type.full Pubblicazioni::01 - Articolo su rivista it
dc.type.impactfactor si it
dc.type.miur 262 en
dc.type.publicationstatus Pubblicato it
dc.type.referee Sì, ma tipo non specificato it
iris.orcid.lastModifiedDate 2023/07/26 13:06:14 *
iris.orcid.lastModifiedMillisecond 1690369574003 *
iris.sitodocente.maxattempts 1 -
iris.unpaywall.metadataCallLastModified 28/07/2023 12:18:55 -
iris.unpaywall.metadataCallLastModifiedMillisecond 1690539535157 -
iris.unpaywall.metadataErrorDescription 0 -
iris.unpaywall.metadataErrorType ERROR_NO_MATCH -
iris.unpaywall.metadataStatus ERROR -
isi.authority.ancejournal ANNALS OF HUMAN BIOLOGY###0301-4460 *
isi.category CU *
isi.category BF *
isi.category NE *
isi.date.issued 2009 *
isi.description.allpeopleoriginal Ottoni, C; Martinez-Labarga, C; Vitelli, L; Scano, G; Fabrini, E; Contini, I; Biondi, G; Rickards, O; *
isi.document.sourcetype WOS.SCI *
isi.document.type Article *
isi.document.typenorm Article *
isi.document.types Article *
isi.identifier.doi 10.3109/03014460903198509 *
isi.identifier.eissn 1464-5033 *
isi.identifier.isi WOS:000272968100010 *
isi.journal.journaltitle ANNALS OF HUMAN BIOLOGY *
isi.journal.journaltitleabbrev ANN HUM BIOL *
isi.language.original English *
isi.publisher.place 2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND *
isi.relation.firstpage 785 *
isi.relation.issue 6 *
isi.relation.lastpage 811 *
isi.relation.volume 36 *
isi.title Human mitochondrial DNA variation in Southern Italy *
scopus.authority.ancejournal ANNALS OF HUMAN BIOLOGY###0301-4460 *
scopus.category 2713 *
scopus.category 1314 *
scopus.category 1302 *
scopus.category 1311 *
scopus.category 2739 *
scopus.contributor.affiliation University of Rome 'Tor Vergata' -
scopus.contributor.affiliation University of Rome 'Tor Vergata' -
scopus.contributor.affiliation University of Rome 'Tor Vergata' -
scopus.contributor.affiliation University of Rome 'Tor Vergata' -
scopus.contributor.affiliation University of Rome 'Tor Vergata' -
scopus.contributor.affiliation University of Rome 'Tor Vergata' -
scopus.contributor.affiliation University of l'Aquila -
scopus.contributor.affiliation University of Rome 'Tor Vergata' -
scopus.contributor.afid 60027509 -
scopus.contributor.afid 60027509 -
scopus.contributor.afid 60027509 -
scopus.contributor.afid 60027509 -
scopus.contributor.afid 60027509 -
scopus.contributor.afid 60027509 -
scopus.contributor.afid 60018783 -
scopus.contributor.afid 60027509 -
scopus.contributor.auid 16836860100 -
scopus.contributor.auid 6602423556 -
scopus.contributor.auid 35742208200 -
scopus.contributor.auid 16195304600 -
scopus.contributor.auid 35740285700 -
scopus.contributor.auid 14122889200 -
scopus.contributor.auid 7006953821 -
scopus.contributor.auid 7003318108 -
scopus.contributor.country Italy -
scopus.contributor.country Italy -
scopus.contributor.country Italy -
scopus.contributor.country Italy -
scopus.contributor.country Italy -
scopus.contributor.country Italy -
scopus.contributor.country Italy -
scopus.contributor.country Italy -
scopus.contributor.dptid 104393123 -
scopus.contributor.dptid 104393123 -
scopus.contributor.dptid 104393123 -
scopus.contributor.dptid 104393123 -
scopus.contributor.dptid 104393123 -
scopus.contributor.dptid 104393123 -
scopus.contributor.dptid 100243910 -
scopus.contributor.dptid 104393123 -
scopus.contributor.name Claudio -
scopus.contributor.name Cristina -
scopus.contributor.name Luciana -
scopus.contributor.name Giuseppina -
scopus.contributor.name Enrico -
scopus.contributor.name Irene -
scopus.contributor.name Gianfranco -
scopus.contributor.name Olga -
scopus.contributor.subaffiliation Department of Biology; -
scopus.contributor.subaffiliation Department of Biology; -
scopus.contributor.subaffiliation Department of Biology; -
scopus.contributor.subaffiliation Department of Biology; -
scopus.contributor.subaffiliation Department of Biology; -
scopus.contributor.subaffiliation Department of Biology; -
scopus.contributor.subaffiliation Department of Environmental Sciences; -
scopus.contributor.subaffiliation Department of Biology; -
scopus.contributor.surname Ottoni -
scopus.contributor.surname Martinez-Labarga -
scopus.contributor.surname Vitelli -
scopus.contributor.surname Scano -
scopus.contributor.surname Fabrini -
scopus.contributor.surname Contini -
scopus.contributor.surname Biondi -
scopus.contributor.surname Rickards -
scopus.date.issued 2009 *
scopus.description.abstract Background: Since prehistoric times Southern Italy has been a cultural crossroads of the Mediterranean basin. Genetic data on the peoples of Basilicata and Calabria are scarce and, particularly, no records on mtDNA variability have been published. Aim: In this study mtDNA haplotypes of populations from Basilicata, Calabria and Sicily are compared with those of other Italian and Mediterranean populations, so as to investigate their genetic relationships. Subjects and methods: A total of 341 individuals was analysed for mtDNA in order to provide their classification into haplogroups. Multivariate analysis was used to compare the studied populations with other Mediterranean samples; median-joining network analysis was applied to observe the relationship between the major lineages of the Southern Italians. Results: The haplogroup distribution in the Southern Italian samples falls within the typical pattern of mtDNA variability of Western Eurasia. The comparison with other Mediterranean countries showed a substantial homogeneity of the area, which is probably related to the historic contact through the Mediterranean Sea. Conclusion: The mtDNA analysis demonstrated that Southern Italy displays a typical pattern of Mediterranean basin variability, even though it appears plausible that Southern Italy was less affected by the effects of the Late Glacial Maximum, which reduced genetic diversity in Europe. © 2009 Informa UK Ltd. *
scopus.description.allpeopleoriginal Ottoni C.; Martinez-Labarga C.; Vitelli L.; Scano G.; Fabrini E.; Contini I.; Biondi G.; Rickards O. *
scopus.differences scopus.description.allpeopleoriginal *
scopus.differences scopus.relation.issue *
scopus.document.type ar *
scopus.document.types ar *
scopus.identifier.doi 10.3109/03014460903198509 *
scopus.identifier.eissn 1464-5033 *
scopus.identifier.pmid 19852679 *
scopus.identifier.pui 355702672 *
scopus.identifier.scopus 2-s2.0-70450240940 *
scopus.journal.sourceid 13035 *
scopus.language.iso eng *
scopus.relation.firstpage 785 *
scopus.relation.issue 6 *
scopus.relation.lastpage 811 *
scopus.relation.volume 36 *
scopus.subject.keywords Coding region; Genetic diversity; Haplogroups; HVS-I; MtDNA; *
scopus.title Human mitochondrial DNA variation in Southern Italy *
scopus.titleeng Human mitochondrial DNA variation in Southern Italy *
Appare nelle tipologie: 01 - Articolo su rivista
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/15570
Citazioni
  • ???jsp.display-item.citation.pmc??? 9
  • Scopus 21
  • ???jsp.display-item.citation.isi??? 20
social impact