The structural features and conformational equilibria of a series of short, linear Cα-methylvaline [(αMe)Val]-based peptides in methanol were investigated by combining fluorescence resonance energy transfer measurements and molecular mechanics data. IR spectra were employed to determine their secondary structure, which exhibits an intramolecularly H-bonded, 310-helix conformation that is affected by backbone distortions that are enhanced by the shortness of the main chain

Pispisa, B., Mazzuca, C., Palleschi, A., Stella, L., Venanzi, M., Formaggio, F., et al. (2002). Structural features and conformational equilibria of 3,10-helical peptides in solution by spectroscopic and molecular mechanics studies. BIOPOLYMERS, 67, 247-250 [10.1002/bip.10118].

Structural features and conformational equilibria of 3,10-helical peptides in solution by spectroscopic and molecular mechanics studies

PISPISA, BASILIO;MAZZUCA, CLAUDIA;PALLESCHI, ANTONIO;STELLA, LORENZO;VENANZI, MARIANO;
2002-01-01

Abstract

The structural features and conformational equilibria of a series of short, linear Cα-methylvaline [(αMe)Val]-based peptides in methanol were investigated by combining fluorescence resonance energy transfer measurements and molecular mechanics data. IR spectra were employed to determine their secondary structure, which exhibits an intramolecularly H-bonded, 310-helix conformation that is affected by backbone distortions that are enhanced by the shortness of the main chain
2002
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore CHIM/02 - CHIMICA FISICA
English
foldamers;Förster energy transfer;time-resolved fluorescence;310 helix
Pispisa, B., Mazzuca, C., Palleschi, A., Stella, L., Venanzi, M., Formaggio, F., et al. (2002). Structural features and conformational equilibria of 3,10-helical peptides in solution by spectroscopic and molecular mechanics studies. BIOPOLYMERS, 67, 247-250 [10.1002/bip.10118].
Pispisa, B; Mazzuca, C; Palleschi, A; Stella, L; Venanzi, M; Formaggio, F; Toniolo, C; Broxterman, Q
Articolo su rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/132970
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