The O subfamily of forkhead (FoxO) 1 is a pivotal element in the regulation of endothelial activation. Compartmentalization and activity of FoxO1 is regulated by post translational modifications, but the implication in endothelial dysfunction and atherosclerosis remain controversial. Our aim was to identify FoxO1 related metabolic signatures in endothelial cells.

Menghini, R., Casagrande, V., Cardellini, M., Ballanti, M., Davato, F., Cardolini, I., et al. (2015). FoxO1 regulates asymmetric dimethylarginine via downregulation of dimethylaminohydrolase 1 in human endothelial cells and subjects with atherosclerosis. ATHEROSCLEROSIS, 242(1), 230-235 [10.1016/j.atherosclerosis.2015.07.026].

FoxO1 regulates asymmetric dimethylarginine via downregulation of dimethylaminohydrolase 1 in human endothelial cells and subjects with atherosclerosis

MENGHINI, ROSSELLA;CARDELLINI, MARINA;BALLANTI, MARTA;FABRIZI, MARTA;ANEMONA, LUCIA;IPPOLITI, ARNALDO;MAURIELLO, ALESSANDRO;FEDERICI, MASSIMO
2015-01-01

Abstract

The O subfamily of forkhead (FoxO) 1 is a pivotal element in the regulation of endothelial activation. Compartmentalization and activity of FoxO1 is regulated by post translational modifications, but the implication in endothelial dysfunction and atherosclerosis remain controversial. Our aim was to identify FoxO1 related metabolic signatures in endothelial cells.
2015
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/49 - SCIENZE TECNICHE DIETETICHE APPLICATE
Settore MED/08 - ANATOMIA PATOLOGICA
English
Con Impact Factor ISI
ADMA; Atherosclerosis; Biomarker; Endothelium; FoxO1
Menghini, R., Casagrande, V., Cardellini, M., Ballanti, M., Davato, F., Cardolini, I., et al. (2015). FoxO1 regulates asymmetric dimethylarginine via downregulation of dimethylaminohydrolase 1 in human endothelial cells and subjects with atherosclerosis. ATHEROSCLEROSIS, 242(1), 230-235 [10.1016/j.atherosclerosis.2015.07.026].
Menghini, R; Casagrande, V; Cardellini, M; Ballanti, M; Davato, F; Cardolini, I; Stoehr, R; Fabrizi, M; Morelli, M; Anemona, L; Bernges, I; Schwedhelm, E; Ippoliti, A; Mauriello, A; Boger, R; Federici, M
Articolo su rivista
File in questo prodotto:
File Dimensione Formato  
1-s2.0-S0021915015300460-main.pdf

solo utenti autorizzati

Descrizione: articolo principale
Licenza: Copyright dell'editore
Dimensione 1.37 MB
Formato Adobe PDF
1.37 MB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/130009
Citazioni
  • ???jsp.display-item.citation.pmc??? 6
  • Scopus 22
  • ???jsp.display-item.citation.isi??? 21
social impact