Human immunodeficiency virus (HIV) chronically infected patients are at increased risk of developing non-Hodgkin lymphoma compared with the general population. Highly active antiretroviral therapy has had a dramatic effect on the natural history of HIV infection, reducing the incidence of acquired immunodeficiency syndrome-related non-Hodgkin lymphoma and improving overall survival. However, problems related to adherence to treatment, frequently experienced during adolescence, may increase the risk of acquired immunodeficiency syndrome-related cancers. Optimizing highly active antiretroviral therapy and monitoring noncompliant patients with persisting HIV replication should be considered by physicians who take care of these patients. We herein report 2 cases of relapsed/progressive Burkitt lymphoma in HIV vertically infected adolescents.

Zangari, P., Santilli, V., Cotugno, N., Manno, E., Palumbo, G., Lombardi, A., et al. (2013). Raising awareness of non-hodgkin lymphoma in HIV-infected adolescents: Report of 2 cases in the HAART era. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 35(3), e134-e137 [10.1097/MPH.0b013e318282cef5].

Raising awareness of non-hodgkin lymphoma in HIV-infected adolescents: Report of 2 cases in the HAART era

Cotugno, N;PALUMBO, GIUSEPPE;Palma, P;
2013-01-01

Abstract

Human immunodeficiency virus (HIV) chronically infected patients are at increased risk of developing non-Hodgkin lymphoma compared with the general population. Highly active antiretroviral therapy has had a dramatic effect on the natural history of HIV infection, reducing the incidence of acquired immunodeficiency syndrome-related non-Hodgkin lymphoma and improving overall survival. However, problems related to adherence to treatment, frequently experienced during adolescence, may increase the risk of acquired immunodeficiency syndrome-related cancers. Optimizing highly active antiretroviral therapy and monitoring noncompliant patients with persisting HIV replication should be considered by physicians who take care of these patients. We herein report 2 cases of relapsed/progressive Burkitt lymphoma in HIV vertically infected adolescents.
2013
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA
English
Adolescent; Antineoplastic Combined Chemotherapy Protocols; Awareness; HIV Infections; HIV-1; Humans; Lymphoma, AIDS-Related; Lymphoma, Non-Hodgkin; Male; Antiretroviral Therapy, Highly Active
Zangari, P., Santilli, V., Cotugno, N., Manno, E., Palumbo, G., Lombardi, A., et al. (2013). Raising awareness of non-hodgkin lymphoma in HIV-infected adolescents: Report of 2 cases in the HAART era. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 35(3), e134-e137 [10.1097/MPH.0b013e318282cef5].
Zangari, P; Santilli, V; Cotugno, N; Manno, E; Palumbo, G; Lombardi, A; De Vito, R; Tchidjou, H; Baldassari, S; Ariganello, P; Pontrelli, G; De Florio, F; Palma, P; Bernardi, S
Articolo su rivista
File in questo prodotto:
File Dimensione Formato  
J Pediatr Hematol Oncol.pdf

accesso aperto

Licenza: Copyright dell'editore
Dimensione 105.71 kB
Formato Adobe PDF
105.71 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/129966
Citazioni
  • ???jsp.display-item.citation.pmc??? 4
  • Scopus 4
  • ???jsp.display-item.citation.isi??? 0
social impact