Mitochondrial DNA from the yeast Kluyveromyces marxianus var. lactis (K.lactis) is a circular molecule of 39 kilobase-pairs. A genetic and physical map was constructed. We found that this genome contained a large number of guanine-cytosine (GC)-rich sequence clusters, many of which are characterized by the presence of SacII restriction sites (CCGCGG). The primary sequence of the GC clusters often showed a palindromic structure. These GC clusters were present in several varieties of K.marxianus, but not in others. The presence of these clusters is a major feature that distinguishes K.lactis strains from those of K.marxianus var. marxianus (including K.fragilis).

Ragnini, A., Fukuhara, H. (1988). Mitochondrial DNA of the yeast Kluyveromyces: guanine-cytosine rich sequence clusters. NUCLEIC ACIDS RESEARCH, 16(17), 8433-8442 [10.1093/nar/16.17.8433].

Mitochondrial DNA of the yeast Kluyveromyces: guanine-cytosine rich sequence clusters

RAGNINI, ANTONELLA;
1988-09-12

Abstract

Mitochondrial DNA from the yeast Kluyveromyces marxianus var. lactis (K.lactis) is a circular molecule of 39 kilobase-pairs. A genetic and physical map was constructed. We found that this genome contained a large number of guanine-cytosine (GC)-rich sequence clusters, many of which are characterized by the presence of SacII restriction sites (CCGCGG). The primary sequence of the GC clusters often showed a palindromic structure. These GC clusters were present in several varieties of K.marxianus, but not in others. The presence of these clusters is a major feature that distinguishes K.lactis strains from those of K.marxianus var. marxianus (including K.fragilis).
12-set-1988
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore BIO/10 - BIOCHIMICA
English
Con Impact Factor ISI
Base Sequence; DNA Restriction Enzymes; DNA, Circular; DNA, Mitochondrial; Kluyveromyces; Molecular Sequence Data; Nucleic Acid Conformation; Saccharomycetales; Cytosine; Genes, Fungal; Guanine
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC338568/
Ragnini, A., Fukuhara, H. (1988). Mitochondrial DNA of the yeast Kluyveromyces: guanine-cytosine rich sequence clusters. NUCLEIC ACIDS RESEARCH, 16(17), 8433-8442 [10.1093/nar/16.17.8433].
Ragnini, A; Fukuhara, H
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/128374
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