In the last decades, evaluation of clinically relevant thrombotic complications in patients with acute leukemia (AL) has been poorly investigated. The authors performed a multi-center study to evaluate the management of symptomatic venous thromboembolism (VTE) in adult patients with AL. The intention was to find as clinically relevant the following: symptomatic Venous Thrombosis (VT) occurred in typical (lower limbs) and atypical (cerebral, upper limbs, abdominal, etc) sites with or without pulmonary embolism (PE). Over a population of 1461 patients with AL, 22 cases of symptomatic VTE were recorded in hospitalized patients with a mean age of 54.6 years. The absolute incidence of VTE was 1.5%. VTE occurred during chemotherapy in 17/22 (77.2%) cases, mainly (14/17, 82.3%) during the induction phase. Treatment of acute VTE was based on Low Molecular Weight Heparin (LMWH) at full dosage for the first month from diagnosis and reduced dosage (75%) for the following month Read More: http://informahealthcare.com/doi/abs/10.3109/10428194.2015.1046864

Napolitano, M., Valore, L., Malato, A., Saccullo, G., Vetro, C., Mitra, M., et al. (2016). Management of venous thromboembolism in patients with acute leukemia at high bleeding risk: a multi-center study. leukemia & lymphoma, 57(1), 116-119 [10.3109/10428194.2015.1046864].

Management of venous thromboembolism in patients with acute leukemia at high bleeding risk: a multi-center study

DEL PRINCIPE, MARIA ILARIA;
2016-01-01

Abstract

In the last decades, evaluation of clinically relevant thrombotic complications in patients with acute leukemia (AL) has been poorly investigated. The authors performed a multi-center study to evaluate the management of symptomatic venous thromboembolism (VTE) in adult patients with AL. The intention was to find as clinically relevant the following: symptomatic Venous Thrombosis (VT) occurred in typical (lower limbs) and atypical (cerebral, upper limbs, abdominal, etc) sites with or without pulmonary embolism (PE). Over a population of 1461 patients with AL, 22 cases of symptomatic VTE were recorded in hospitalized patients with a mean age of 54.6 years. The absolute incidence of VTE was 1.5%. VTE occurred during chemotherapy in 17/22 (77.2%) cases, mainly (14/17, 82.3%) during the induction phase. Treatment of acute VTE was based on Low Molecular Weight Heparin (LMWH) at full dosage for the first month from diagnosis and reduced dosage (75%) for the following month Read More: http://informahealthcare.com/doi/abs/10.3109/10428194.2015.1046864
2016
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/15 - MALATTIE DEL SANGUE
English
Con Impact Factor ISI
Napolitano, M., Valore, L., Malato, A., Saccullo, G., Vetro, C., Mitra, M., et al. (2016). Management of venous thromboembolism in patients with acute leukemia at high bleeding risk: a multi-center study. leukemia & lymphoma, 57(1), 116-119 [10.3109/10428194.2015.1046864].
Napolitano, M; Valore, L; Malato, A; Saccullo, G; Vetro, C; Mitra, M; Fabbiano, F; Mannina, D; Casuccio, A; Lucchesi, A; DEL PRINCIPE, Mi; Candoni, A; Di Raimondo, F; Siragusa, S
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/114382
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