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Data di pubblicazione Titolo Autore(i) Tipo File
1-gen-2005 Oral administration of PARP inhibitor GPI 18180 increases the anti-tumor activity of temozolomide against intracranial melanoma in mice. Lapidus, R; Tentori, L; Graziani, G; Leonetti, C; Scarsella, M; Vergati, M; Muzi, A; Zhang, J; and the Guilford PARP Project, G Intervento a convegno
1-gen-2005 Gli inibitori della poli (ADP-ribosio) polimerasi (PARP) per superare la chemioresistenza a metilanti e inibitori di topoisomerasi I Tentori, L; Leonetti, C; Scarsella, M; Vergati, M; Muzi, A; Forini, O; Xu, W; Zhang, J; Graziani, G Intervento a convegno
1-apr-2005 Role of PARP, NF-kB and telomerase in necrosis induced by selective methylation of N3-adenine. Tentori, L; Forini, O; Muzi, A; Vergati, M; Gold, B; Graziani, G Intervento a convegno
1-ago-2005 Generation of an immortalized human endothelial cell line as a model of neovascular proliferating endothelial cells to assess chemosensitivity to anticancer drugs. Tentori, L; Vergati, M; Muzi, A; Levati, L; Ruffini, F; Forini, O; Vernole, P; Lacal, Pm; Graziani, G Articolo su rivista
1-dic-2005 Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide Tentori, L; Leonetti, C; Scarsella, M; Muzi, A; Vergati, M; Forini, O; Lacal, P; Ruffini, F; Gold, B; Li, W; Zhang, J; Graziani, G Articolo su rivista
1-ago-2006 Inhibition of poly(ADP-ribose) polymerase prevents irinotecan-induced intestinal damage and enhances irinotecan/temozolomide efficacy against colon carcinoma. Tentori, L; Leonetti, C; Scarsella, M; Muzi, A; Mazzon, E; Vergati, M; Forini, O; Lapidus, R; Xu, W; Dorio, As; Zhang, J; Cuzzocrea, S; Graziani, G Articolo su rivista
1-gen-2007 Targeting angiogenesis with poly(ADP-ribose) polymerase inhibitors Muzi, A; Lacal, P; Dorio, As; Ruffini, F; Scarsella, M; Leonetti, C; Xu, W; Zhang, J; Tentori, L; Graziani, G Intervento a convegno
1-gen-2007 Poly(ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis Tentori, L; Lacal, P; Muzi, A; Dorio, As; Leonetti, C; Scarsella, M; Ruffini, F; Min, W; Stoppacciaro, A; Colarossi, C; Wang, Z; Zhang, J; Graziani, G Articolo su rivista
1-gen-2007 Evidence that corticotropin-releasing hormone inhibits cell growth of human breast cancer cells via the activation of CRH-R1 receptor subtype. Graziani, G; Tentori, L; Muzi, A; Vergati, M; Tringali, G; Pozzoli, G; Navarra, P Articolo su rivista
1-gen-2008 Pharmacological inhibition of poly (ADP-ribose) polymerase (PARP) activity down-regulates the expression of syndecan-4 and Id-1 in endothelial cells and increases temozolomide sensitivity of PARP-1 silenced melanoma cells. Dorio, As; Muzi, A; Lacal, P; Ruffini, F; Shah, G; Zhang, J; Tentori, L; Graziani, G Intervento a convegno
1-gen-2008 Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity to temozolomide. 17th International Symposium on poly(ADP-ribosyl)ation. Tentori, L; Muzi, A; Dorio, As; Mazzon, E; Lacal, P; Shah, G; Zhang, J; Nocentini, G; Cuzzocrea, S; Graziani, G Intervento a convegno
1-gen-2008 Valproic acid activity in androgen-sensitive and -insensitive human prostate cancer cells Iacopino, F; Urbano, R; Graziani, G; Muzi, A; Navarra, P; Sica, G Articolo su rivista
1-apr-2008 The integrin antagonist cilengitide increases the antitumor activity of temozolomide against malignant melanoma Tentori, L; Dorio, As; Muzi, A; Lacal, Pm; Ruffini, F; Navarra, P; Graziani, G Articolo su rivista
1-giu-2008 Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity Tentori, L; Muzi, A; Dorio, As; Bultrini, S; Mazzon, E; Lacal, P; Shah, G; Zhang, J; Navarra, P; Nocentini, G; Cuzzocrea, S; Graziani, G Articolo su rivista
1-mar-2009 Pharmacological inhibition of poly(ADP-ribose) polymerase activity down-regulates the expression of syndecan-4 and Id-1 in endothelial cells Lacal, Pm; Tentori, L; Muzi, A; Ruffini, F; Dorio, As; Xu, W; Arcelli, D; Zhang, J; Graziani, G Articolo su rivista
1-nov-2009 Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant Fiorani, P; Tesauro, C; Mancini, G; Chillemi, G; D'Annessa, I; Graziani, G; Tentori, L; Muzi, A; Desideri, A Articolo su rivista
1-gen-2010 Novel Glutathione S-Transferase Inhibitor Enhances Temozolomide Efficacy Against Malignant Melanoma 52nd Annual Meeting of the Italian Cancer Society. Lost in translation: bridging the gap between cancer research and effective therapies Tentori, L; Dorio, As; Mazzon, E; Muzi, A; Saua, A; Cuzzocrea, S; Federici, G; Caccuri, Am; Graziani, G Intervento a convegno
1-giu-2010 Pharmacological Inhibition of Poly(ADP-ribose) Polymerase (PARP) Activity in PARP-1 Silenced Tumour Cells Increases Chemosensitivity to Temozolomide and to a N3-Adenine Selective Methylating Agent. Tentori, L; Muzi, A; Dorio, As; Scarsella, M; Leonetti, C; Shah, G; Xu, W; Camaioni, E; Gold, B; Pellicciari, R; Dantzer, F; Zhang, J; Graziani, G Articolo su rivista
1-gen-2011 Placenta growth factor induces melanoma resistance to temozolomide through a mechanism that involves the activation of the transcription factor NF-κB Levati, L; Ruffini, F; Muzi, A; Umezawa, K; Graziani, G; D'Atri, S; Lacal, P Articolo su rivista
15-gen-2011 Poly(ADP-ribose) polymerase signaling of topoisomerase 1-dependent DNA damage in carcinoma cells D'Onofrio, G; Tramontano, F; Dorio, As; Muzi, A; Maselli, V; Fulgione, D; Graziani, G; Malanga, M; Quesada, P Articolo su rivista
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