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Please use this identifier to cite or link to this item: http://hdl.handle.net/2108/15570

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dc.contributor.authorMARTINEZ-LABARGA, MARIA CRISTINAit
dc.contributor.authorSCANO, GIUSEPPINAit
dc.contributor.authorCONTINI, IRENEit
dc.contributor.authorRICKARDS, OLGAit
dc.date.issued2009-
dc.date.available2011-08-30T09:41:04Z-
dc.date.accessioned2011-08-30T09:41:04Z-
dc.description.abstractBackground: Since prehistoric times Southern Italy has been a cultural crossroads of the Mediterranean basin. Genetic data on the peoples of Basilicata and Calabria are scarce and, particularly, no records on mtDNA variability have been published. Aim: In this study mtDNA haplotypes of populations from Basilicata, Calabria and Sicily are compared with those of other Italian and Mediterranean populations, so as to investigate their genetic relationships. Subjects and methods: A total of 341 individuals was analysed for mtDNA in order to provide their classification into haplogroups. Multivariate analysis was used to compare the studied populations with other Mediterranean samples; median-joining network analysis was applied to observe the relationship between the major lineages of the Southern Italians. Results: The haplogroup distribution in the Southern Italian samples falls within the typical pattern of mtDNA variability of Western Eurasia. The comparison with other Mediterranean countries showed a substantial homogeneity of the area, which is probably related to the historic contact through the Mediterranean Sea. Conclusion: The mtDNA analysis demonstrated that Southern Italy displays a typical pattern of Mediterranean basin variability, even though it appears plausible that Southern Italy was less affected by the effects of the Late Glacial Maximum, which reduced genetic diversity in Europe.it
dc.description.allauthorsOttoni, C; Martinez-Labarga, C; Vitelli, L; Scano, G; Fabrini, E; Contini, I; Biondi, G; Rickards, Oit
dc.description.numberofauthors8it
dc.identifier.citationOttoni, C., Martinez-Labarga, C., Vitelli, L., Scano, G., Fabrini, E., Contini, I., et al. (2009). Human mitochondrial DNA variation in Southern Italy. Annals of human biology, 36, 785-811.it
dc.identifier.doi10.3109/03014460903198509it
dc.identifier.urlhttp://dx.doi.org/10.3109/03014460903198509it
dc.language.isoengit
dc.publisher.countryGBit
dc.publisher.nameTaylor & Francisit
dc.relation.firstpage785it
dc.relation.ispartofAnnals of human biologyit
dc.relation.issn0301-4460it
dc.relation.lastpage811it
dc.relation.volume36it
dc.subject.keywordsmtDNA; HVS-I; coding region; genetic diversity; haplogroupsit
dc.subject.miurSettore BIO/08 - Antropologiait
dc.titleHuman mitochondrial DNA variation in Southern Italyit
dc.type.circulationRilevanza internazionaleit
dc.type.contributionArticoloit
dc.type.impactfactorCon Impact Factor ISIit
dc.type.publicationstatusPubblicatoit
dc.type.refereeSì, ma tipo non specificatoit
dc.typeArticolo su rivistait
dc.identifier.urihttp://hdl.handle.net/2108/15570-
dc.subject.isicruiBiologia Molecolare e Geneticait
dc.description.departmentDipartimento di Biologiait
dc.description.fulltextnoneen
dc.identifier.isiWOS:000272968100010en
dc.identifier.scopushttp://www.scopus.com/inward/record.url?eid=2-s2.0-70450240940&partnerID=40&md5=f7a6fb483d06dc0960b83c81bb126aeden
dc.identifier.pmid19852679en
Appears in Collections:Pubblicazioni >01 - Articolo su rivista

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